A theoretical study of the detection of activated position in cerebral cortex from NIR signal

Y. Kashio, Eiji Okada

研究成果: Conference contribution

抄録

Near infrared (NIR) spectroscopy and imaging have been applied to measure oxygenation change in the brain. Multi-channel NIR system can obtain topographic image of brain function. However poor spatial resolution due to tissue scattering is serious problem of NIR imaging. In this study, we propose a simple method to estimate the centre of the absorption change in the brain from the signal detected with multichannel NIR system. The theoretical analysis of photon measurement density functions for the adjoining source-detector pairs in multi-channel NIR system suggests that the difference in intensity between the adjoining source-detector pairs almost linearly relates with the position of the absorption perturbation. The proposed method to estimate the centre of the absorption change in the brain is evaluated by using three layered head model. The estimated position is almost consistent with the centre of the absorption change. In case where the broad absorption change occurred close to the edge of the measuring region, the estimated position tends to be shifted inward of the measuring region.

元の言語English
ホスト出版物のタイトルProceedings of SPIE - The International Society for Optical Engineering
編集者B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraka
ページ462-469
ページ数8
4250
DOI
出版物ステータスPublished - 2001
イベントOptical Tomography and Spectroscopy of Tissue IV - San Jose, CA, United States
継続期間: 2001 1 212001 1 23

Other

OtherOptical Tomography and Spectroscopy of Tissue IV
United States
San Jose, CA
期間01/1/2101/1/23

Fingerprint

cerebral cortex
Brain
brain
Infrared radiation
Infrared imaging
Detectors
Near infrared spectroscopy
Oxygenation
Probability density function
oxygenation
detectors
Light sources
estimates
Photons
Scattering
Tissue
spatial resolution
infrared spectroscopy
perturbation
photons

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

これを引用

Kashio, Y., & Okada, E. (2001). A theoretical study of the detection of activated position in cerebral cortex from NIR signal. : B. Chance, R. R. Alfano, B. J. Tromberg, M. Tamura, & E. M. Sevick-Muraka (版), Proceedings of SPIE - The International Society for Optical Engineering (巻 4250, pp. 462-469) https://doi.org/10.1117/12.434483

A theoretical study of the detection of activated position in cerebral cortex from NIR signal. / Kashio, Y.; Okada, Eiji.

Proceedings of SPIE - The International Society for Optical Engineering. 版 / B. Chance; R.R. Alfano; B.J. Tromberg; M. Tamura; E.M. Sevick-Muraka. 巻 4250 2001. p. 462-469.

研究成果: Conference contribution

Kashio, Y & Okada, E 2001, A theoretical study of the detection of activated position in cerebral cortex from NIR signal. : B Chance, RR Alfano, BJ Tromberg, M Tamura & EM Sevick-Muraka (版), Proceedings of SPIE - The International Society for Optical Engineering. 巻. 4250, pp. 462-469, Optical Tomography and Spectroscopy of Tissue IV, San Jose, CA, United States, 01/1/21. https://doi.org/10.1117/12.434483
Kashio Y, Okada E. A theoretical study of the detection of activated position in cerebral cortex from NIR signal. : Chance B, Alfano RR, Tromberg BJ, Tamura M, Sevick-Muraka EM, 編集者, Proceedings of SPIE - The International Society for Optical Engineering. 巻 4250. 2001. p. 462-469 https://doi.org/10.1117/12.434483
Kashio, Y. ; Okada, Eiji. / A theoretical study of the detection of activated position in cerebral cortex from NIR signal. Proceedings of SPIE - The International Society for Optical Engineering. 編集者 / B. Chance ; R.R. Alfano ; B.J. Tromberg ; M. Tamura ; E.M. Sevick-Muraka. 巻 4250 2001. pp. 462-469
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