A thirst for enantioselectivity in catalytic addition of alkylnitriles

Naoya Kumagai, Masakatsu Shibasaki

研究成果: Review article査読

抄録

This Highlight Review sheds light on a neglected aspect of alkylnitriles in synthetic organic chemistry. The chemical inertness and highly polar nature of alkylnitriles have particular utility as a reaction solvent. Alkylnitriles, however, also serve as potential building blocks for constructing carbon frameworks of interest. Two decades of exploratory studies of this elusive reaction revealed competent catalytic systems that allow for catalytic and enantioselective coupling of alkylnitriles with electrophiles.

本文言語English
ページ(範囲)1322-1327
ページ数6
ジャーナルChemistry Letters
48
11
DOI
出版ステータスPublished - 2019
外部発表はい

ASJC Scopus subject areas

  • 化学 (全般)

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