Abetalipoproteinemia-like lipid profile and acanthocytosis in a young woman with anorexia nervosa

Jun Takeshita, Yasumichi Arai, Nobuyoshi Hirose, Hideko Tsukamoto, Joichiro Shirahase

研究成果: Article査読

1 被引用数 (Scopus)

抄録

We report the case of a 17-year-old woman with anorexia nervosa (AN) who developed an abetalipoproteinemia-like lipid profile and acanthocytosis. These abnormalities resolved slowly as her nutritional status improved. We considered 3 possible causes of an abetalipoproteinemia-like lipid profile in AN: (1) depletion of hepatic substrate for apolipoprotein B synthesis, (2) lack of exogenous fatty acids with exhaustion of endogenous stores of triglycerides in adipose tissue, and (3) preservation of the lipoprotein lipase (LPL) mass. This unusual case provides important clues that enhance our understanding of lipid metabolism under exogenous and endogenous fat deprivation and highlights the pivotal role of LPL as a gatekeeper of the energy source.

本文言語English
ページ(範囲)281-284
ページ数4
ジャーナルAmerican Journal of the Medical Sciences
324
5
DOI
出版ステータスPublished - 2002 11

ASJC Scopus subject areas

  • Medicine(all)

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