Access to Tetronic Acids via Silver-Catalyzed CO2 Incorporation into Conjugated Ynones

Yuta Sadamitsu, Keiichi Komatsuki, Kodai Saito, Tohru Yamada

研究成果: Article査読

33 被引用数 (Scopus)

抄録

Facile and versatile access to highly functionalized tetronic acids has been successfully achieved through the reaction of conjugated ynones with carbon dioxide. In the presence of a base, the enolates generated from the ynones capture CO2 via a carbon-carbon bond-forming reaction, accompanied by a 5-exo-dig cyclization reaction of the resulting carboxylate to the alkyne, activated by a silver catalyst. The present method should be applicable to the synthesis of a wide variety of tetronic acids.

本文言語English
ページ(範囲)3191-3194
ページ数4
ジャーナルOrganic Letters
19
12
DOI
出版ステータスPublished - 2017 6月 16

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

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