Acute visual field defect following vitrectomy determined to originate from optic nerve by electrophysiological tests

Atsuro Uchida, Kei Shinoda, Celso Soiti Matsumoto, Miho Kawai, Sayaka Kawai, Hisao Ohde, Yoko Ozawa, Susumu Ishida, Makoto Inoue, Atsushi Mizota, Kazuo Tsubota

研究成果: Article

6 引用 (Scopus)

抄録

Purpose: To present our findings on the cause of an acute visual field defect (VFD) that developed in a patient on the day after vitrectomy for proliferative diabetic retinopathy. Case: A 50-year-old man complained of a blind area in the superior visual field that developed one day after vitrectomy. The patient had undergone uncomplicated vitrectomy for a long-duration vitreous hemorrhage associated with proliferative diabetic retinopathy. Residual vitreous hemorrhage hampered a clear view of the fundus. Goldmann perimetry showed a horizontal VFD in the superior field. The area corresponding to the VFD was examined by multifocal electroretinograms (mfERGs) and multifocal visual evoked potentials (mfVEPs). The amplitudes of the mfVEPs were reduced with prolonged implicit times especially when the superior hemifield was stimulated, while the amplitudes and implicit times were within the normal range when other parts of the visual field were stimulated. In addition, the full-field photopic ERGs and photopic negative responses were attenuated in the right eye. These findings suggested that the VFD did not originate from alterations in the retinal inner and middle layer but in the ganglion cells. The visual acuity improved to 1.2 but his optic disc became pale and the VFD remained unchanged more than 12 years after the surgery. Conclusion: We suggest that vitrectomy can cause ischemic optic neuropathy by interfering with the circulation associated with diabetes mellitus. Evaluations by mfERGs, mfVEPs, and full-field photopic ERGs were helpful in making the diagnosis.

元の言語English
ページ(範囲)396-405
ページ数10
ジャーナルCase Reports in Ophthalmology
3
発行部数3
DOI
出版物ステータスPublished - 2012

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Vitrectomy
Optic Nerve
Visual Fields
Visual Evoked Potentials
Vitreous Hemorrhage
Diabetic Retinopathy
Ischemic Optic Neuropathy
Visual Field Tests
Optic Disk
Ganglia
Visual Acuity
Diabetes Mellitus
Reference Values

ASJC Scopus subject areas

  • Ophthalmology

これを引用

Acute visual field defect following vitrectomy determined to originate from optic nerve by electrophysiological tests. / Uchida, Atsuro; Shinoda, Kei; Matsumoto, Celso Soiti; Kawai, Miho; Kawai, Sayaka; Ohde, Hisao; Ozawa, Yoko; Ishida, Susumu; Inoue, Makoto; Mizota, Atsushi; Tsubota, Kazuo.

:: Case Reports in Ophthalmology, 巻 3, 番号 3, 2012, p. 396-405.

研究成果: Article

Uchida, A, Shinoda, K, Matsumoto, CS, Kawai, M, Kawai, S, Ohde, H, Ozawa, Y, Ishida, S, Inoue, M, Mizota, A & Tsubota, K 2012, 'Acute visual field defect following vitrectomy determined to originate from optic nerve by electrophysiological tests', Case Reports in Ophthalmology, 巻. 3, 番号 3, pp. 396-405. https://doi.org/10.1159/000345507
Uchida, Atsuro ; Shinoda, Kei ; Matsumoto, Celso Soiti ; Kawai, Miho ; Kawai, Sayaka ; Ohde, Hisao ; Ozawa, Yoko ; Ishida, Susumu ; Inoue, Makoto ; Mizota, Atsushi ; Tsubota, Kazuo. / Acute visual field defect following vitrectomy determined to originate from optic nerve by electrophysiological tests. :: Case Reports in Ophthalmology. 2012 ; 巻 3, 番号 3. pp. 396-405.
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AU - Uchida, Atsuro

AU - Shinoda, Kei

AU - Matsumoto, Celso Soiti

AU - Kawai, Miho

AU - Kawai, Sayaka

AU - Ohde, Hisao

AU - Ozawa, Yoko

AU - Ishida, Susumu

AU - Inoue, Makoto

AU - Mizota, Atsushi

AU - Tsubota, Kazuo

PY - 2012

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N2 - Purpose: To present our findings on the cause of an acute visual field defect (VFD) that developed in a patient on the day after vitrectomy for proliferative diabetic retinopathy. Case: A 50-year-old man complained of a blind area in the superior visual field that developed one day after vitrectomy. The patient had undergone uncomplicated vitrectomy for a long-duration vitreous hemorrhage associated with proliferative diabetic retinopathy. Residual vitreous hemorrhage hampered a clear view of the fundus. Goldmann perimetry showed a horizontal VFD in the superior field. The area corresponding to the VFD was examined by multifocal electroretinograms (mfERGs) and multifocal visual evoked potentials (mfVEPs). The amplitudes of the mfVEPs were reduced with prolonged implicit times especially when the superior hemifield was stimulated, while the amplitudes and implicit times were within the normal range when other parts of the visual field were stimulated. In addition, the full-field photopic ERGs and photopic negative responses were attenuated in the right eye. These findings suggested that the VFD did not originate from alterations in the retinal inner and middle layer but in the ganglion cells. The visual acuity improved to 1.2 but his optic disc became pale and the VFD remained unchanged more than 12 years after the surgery. Conclusion: We suggest that vitrectomy can cause ischemic optic neuropathy by interfering with the circulation associated with diabetes mellitus. Evaluations by mfERGs, mfVEPs, and full-field photopic ERGs were helpful in making the diagnosis.

AB - Purpose: To present our findings on the cause of an acute visual field defect (VFD) that developed in a patient on the day after vitrectomy for proliferative diabetic retinopathy. Case: A 50-year-old man complained of a blind area in the superior visual field that developed one day after vitrectomy. The patient had undergone uncomplicated vitrectomy for a long-duration vitreous hemorrhage associated with proliferative diabetic retinopathy. Residual vitreous hemorrhage hampered a clear view of the fundus. Goldmann perimetry showed a horizontal VFD in the superior field. The area corresponding to the VFD was examined by multifocal electroretinograms (mfERGs) and multifocal visual evoked potentials (mfVEPs). The amplitudes of the mfVEPs were reduced with prolonged implicit times especially when the superior hemifield was stimulated, while the amplitudes and implicit times were within the normal range when other parts of the visual field were stimulated. In addition, the full-field photopic ERGs and photopic negative responses were attenuated in the right eye. These findings suggested that the VFD did not originate from alterations in the retinal inner and middle layer but in the ganglion cells. The visual acuity improved to 1.2 but his optic disc became pale and the VFD remained unchanged more than 12 years after the surgery. Conclusion: We suggest that vitrectomy can cause ischemic optic neuropathy by interfering with the circulation associated with diabetes mellitus. Evaluations by mfERGs, mfVEPs, and full-field photopic ERGs were helpful in making the diagnosis.

KW - Ischemic optic neuropathy

KW - Multifocal electroretinogram

KW - Multifocal visual evoked potentials

KW - Photopic negative response

KW - Proliferative diabetic retinopathy

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