Adult head modelling based on time-resolved measurement for NIR instrument

S. Misonoo, E. Okada

    研究成果: Conference article査読

    2 被引用数 (Scopus)

    抄録

    The accurate forward modelling of light propagation in tissue to estimate the partial optical path length in the brain is important for quantitative optical spectroscopy and optical imaging. In this study design of simplified adult head model is investigated to estimate the partial optical path length in the brain. We consider homogeneous, two and three layered models as the simplified models. The apparent optical properties of surface layer of the simplified model are determined by TPSFs at small source-detector separations. Since it is difficult to determine the optical properties of the brain from the in-vivo time-resolved measurement, the optical properties of the brain are assumed to be the reported data. The proposed modelling is evaluated by Monte Carlo simulation. The TPSFs of the five layered models that consist of the scalp, skull, CSF, grey matter and white matter are predicted by Monte Carlo simulation. The apparent optical properties of the surface layer are estimated from the TPSFs for five layered adult head model, and the partial optical path length in the brain is predicted from the proposed simplified models. The predicted partial optical path length is compared with that calculated from the five layered model to evaluate the proposed modelling.

    本文言語English
    ページ(範囲)522-529
    ページ数8
    ジャーナルProceedings of SPIE - The International Society for Optical Engineering
    4250
    DOI
    出版ステータスPublished - 2001 1月 1
    イベントOptical Tomography and Spectroscopy of Tissue IV - San Jose, CA, United States
    継続期間: 2001 1月 212001 1月 23

    ASJC Scopus subject areas

    • 電子材料、光学材料、および磁性材料
    • 凝縮系物理学
    • コンピュータ サイエンスの応用
    • 応用数学
    • 電子工学および電気工学

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