Affinity discrimination of DNA on SPR sensor using oligolysine-immobilized particle

Kaori Umehara, Kazunobu Toshima, Haruma Kawaguchi

研究成果: Paper査読

抄録

We have made an attempt to detect bulge DNA by surface plasmon resonance (SPR) biosensor. Peptide nucleic acid (PNA) was conjugated onto polymeric microsphere, which had been prepared by soap-free emulsion polymerization. SPR results indicated that PNA-conjugated microsphere can detect bulge DNA, and amplify SPR signal. Furthermore, we succeeded in magnifying SPR response more than ten times maintaining high discrimination ability by oligolysine-PNA immobilized microsphere.

本文言語English
ページ数1
出版ステータスPublished - 2006 10 19
イベント55th SPSJ Annual Meeting - Nagoya, Japan
継続期間: 2006 5 242006 5 26

Other

Other55th SPSJ Annual Meeting
国/地域Japan
CityNagoya
Period06/5/2406/5/26

ASJC Scopus subject areas

  • 工学(全般)

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