Aggrecanase analysis of synovial fluid of temporomandibular joint disorders

K. Yoshida, S. Takatsuka, A. Tanaka, E. Hatada, H. Nakamura, K. Nakagawa, Y. Okada

研究成果: Article査読

9 被引用数 (Scopus)

抄録

OBJECTIVES: To determine whether or not aggrecanase in synovial fluid can be used as a biochemical marker in the diagnosis of temporomandibular joint disorder (TMJD). MATERIALS AND METHODS: Forty-four samples of synovial fluid were obtained from 35 patients with internal derangement or osteoarthritis and 15 control samples from 1O asymptomatic volunteers. Aggrecanase in the synovial fluid was examined by immunoblotting. RESULT: The incidence of aggrecanase expression in TMJD group were significantly higher than that in the normal control group (P < 0.05). Those with severe OA and anterior disc displacement without reduction showed significantly high expression of aggrecanase compared with other disease subgroups (P < 0.05). CONCLUSION: These findings suggested that aggrecanase could be a potential biochemical marker for cartilage degeneration in the TMJD.

本文言語English
ページ(範囲)299-302
ページ数4
ジャーナルOral Diseases
11
5
DOI
出版ステータスPublished - 2005 9
外部発表はい

ASJC Scopus subject areas

  • 耳鼻咽喉科学
  • 歯科学(全般)

フィンガープリント

「Aggrecanase analysis of synovial fluid of temporomandibular joint disorders」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル