Alignment-based approach for durable data storage into living organisms

Nozomu Yachie, Kazuhide Sekiyama, Junichi Sugahara, Yoshiaki Ohashi, Masaru Tomita

研究成果: Article査読

43 被引用数 (Scopus)

抄録

The practical realization of DNA data storage is a major scientific goal. Here we introduce a simple, flexible, and robust data storage and retrieval method based on sequence alignment of the genomic DNA of living organisms. Duplicated data encoded by different oligonucleotide sequences was inserted redundantly into multiple loci of the Bacillus subtilis genome. Multiple alignment of the bit data sequences decoded by B. subtilis genome sequences enabled the retrieval of stable and compact data without the need for template DNA, parity checks, or error-correcting algorithms. Combined with the computational simulation of data retrieval from mutated message DNA, a practical use of this alignment-based method is discussed.

本文言語English
ページ(範囲)501-505
ページ数5
ジャーナルBiotechnology Progress
23
2
DOI
出版ステータスPublished - 2007 3 1

ASJC Scopus subject areas

  • Biotechnology

フィンガープリント 「Alignment-based approach for durable data storage into living organisms」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル