Allergic conjunctivitis and dry eye

Hiroshi Fujishima, Ikuko Toda, Jun Shimazaki, Kazuo Tsubota

研究成果: Article査読

54 被引用数 (Scopus)

抄録

Aims - Differential diagnosis of allergic conjunctivitis or dry eye is sometimes very difficult to diagnose by symptoms and clinical examination alone, especially in older patients. It was hypothesised that clinically allergic patients who were serum antigen specific IgE negative were candidates for dry eye. Method - Sixty patients were studied prospectively who were clinically diagnosed with allergic conjunctivitis by their itchy sensation and papilla formation of conjunctiva. They consisted of 30 serum antigen specific IgE positive and 30 IgE negative patients, with no significant differences in age. Dry eye examination and serum total IgE were performed on these two groups. Results - No significant differences were seen between the two groups with regard to age (p = 0.76) and sex ratio. The antibody negative group had lower Schirmer's test scores (p = 0.002), lower tear clearance (p = 0.0001), lower tear function index (p = 0.0001), and lower serum total IgE (p = 0.04), than the antibody positive group. Conclusion-This study suggests that the evaluation of serum antigen specific IgE and tear: dynamics are important for the differential diagnosis of patients with allergic conjunctivitis and dry eye. Clinically diagnosed allergic conjunctivitis with negative serum antigen specific and total IgE can be one form of dry eye.

本文言語English
ページ(範囲)994-997
ページ数4
ジャーナルBritish Journal of Ophthalmology
80
11
DOI
出版ステータスPublished - 1996
外部発表はい

ASJC Scopus subject areas

  • 眼科学
  • 感覚系
  • 細胞および分子神経科学

フィンガープリント

「Allergic conjunctivitis and dry eye」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル