Allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia--recent progress

Shinichiro Okamoto

研究成果: Review article査読

抄録

Allogeneic stem cell transplantation represents the most active form of anti-leukemic therapy in acute myeloid leukemia (AML). Advances in the transplant technology, availability of hematopoietic stem cells and supportive care not only have resulted in improved outcomes but also expanded the transplant options. However, post-transplant relapse and transplant-related mortality, especially those associated with allo-immune reaction after transplantation, remain as the leading causes of failure of this therapeutic approach. This review is going to focus on the recent progress to selectively enhance the anti-AML activity of conditioning and post-transplant allo-immune reaction.

本文言語English
ページ(範囲)1944-1950
ページ数7
ジャーナルNippon rinsho. Japanese journal of clinical medicine
67
10
出版ステータスPublished - 2009 10

ASJC Scopus subject areas

  • 医学(全般)

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