Amounts of proteins altered by mutations in the dnaA gene of Escherichia coli

Akiko Ohba, Tohru Mizushima, Tsutomu Katayama, Kazuhisa Sekimizu

研究成果: Article査読

6 被引用数 (Scopus)

抄録

We identified proteins whose amounts were altered in a temperature-sensitive dnaA46 mutant of Escherichia coli. Proteins whose amounts were increased in the mutant were serine hydroxymethyltransferase, β-ketoacyl [acyl carrier protein] synthase II, long-chain fatty acid transport protein, and UDP-glucose 4-epimerase, while the decreased ones were flagellin and D-ribose-binding protein. Transformation of the mutant with a plasmid containing the wild type dnaA gene complemented the phenotype. As pulse-labeling experiments revealed that the rates of synthesis of the proteins were altered in the mutant, DnaA protein may be involved in expression of these proteins.

本文言語English
ページ(範囲)125-128
ページ数4
ジャーナルFEBS Letters
404
2-3
DOI
出版ステータスPublished - 1997 3 10

ASJC Scopus subject areas

  • 生物理学
  • 構造生物学
  • 生化学
  • 分子生物学
  • 遺伝学
  • 細胞生物学

フィンガープリント

「Amounts of proteins altered by mutations in the dnaA gene of Escherichia coli」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル