An Acidic Polysaccharide Having Activity on the Reticuloendothelial System from the Roots and Rhizomes of Saposhnikovia divaricata

Noriko Shimizu, Masashi Tomoda, Ryoko Gonda, Mieko Kanari

研究成果: Article査読

22 被引用数 (Scopus)

抄録

An acidic polysaccharide, named saposhnikovan C, was isolated from the roots and rhizomes of Saposhnikovia divaricata schischk. It was homogeneous as judged by electrophoresis and gel chromatography, and showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test. It is composed of D-galacturonic acid: L-rhamnose: L-arabinose: D-galactose in a molar ratio of 27:7:8:8, and its molecular mass was estimated to be 132000. About 30 % of the D-galacturonic acid residues exist as the methyl esters. O-Acetyl groups were identified, and the content amounted to 3.3%. Methylation analysis, carbon-13 nuclear magnetic resonance, and controlled Smith degradation studies indicated the structural features. It has a pectin-like rhamnogalacturonan backbone with branched arabinan and galactan side chains.

本文言語English
ページ(範囲)3054-3057
ページ数4
ジャーナルChemical and Pharmaceutical Bulletin
37
11
DOI
出版ステータスPublished - 1989

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

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