An autopsy case of candidal myocardial abscess in a patient with pneumonia

Takayuki Ogura, Hidenori Takahashi, Kosyu Ohkubo, Akihiko Sudoh, Atsushi Chiyotani, Ichiro Nakachi, Yoshishige Kimura, Atsushi Tajima, Hidefumi Koh, Yohei Masugi

研究成果: Article

抄録

A 69-year-old man was admitted to our hospital because of acute respiratory failure and pneumonia. Mechanical ventilation was begun, and antibiotics were subsequently administered. Bronchoalveolar lavage fluid showed fresh blood-like fluid containing hemosiderin-laden macrophages. ANCA and Anti GBM Ab were negative. Finally he was diagnosed with alveolar hemorrhage due to severe pneumonia. After receiving corticosteroid and antibiotics, respiratory failure was improved. One week after extubation, he suddenly developed fever and disturbance of consciousness. Candida albicans was detected from blood and cerebrospinal fluid culture. Despite administration of an antifungal agent, his condition worsened and he died five days after developing fever. Microscopic findings of the autopsy revealed candidal myocardial abscess. We encountered a rare autopsy case of candidal myocardial abscess in non-hematologic disease. This is an important case report to investigate how to diagnose fungal infections and treat them immediately.

元の言語English
ページ(範囲)670-677
ページ数8
ジャーナルJapanese Journal of Chest Diseases
72
発行部数6
出版物ステータスPublished - 2013

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Respiratory Insufficiency
Abscess
Autopsy
Pneumonia
Fever
Anti-Bacterial Agents
Hemosiderin
Antineutrophil Cytoplasmic Antibodies
Mycoses
Antifungal Agents
Bronchoalveolar Lavage Fluid
Consciousness
Candida albicans
Artificial Respiration
Cerebrospinal Fluid
Adrenal Cortex Hormones
Macrophages
Hemorrhage
antiglomerular basement membrane antibody

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

これを引用

Ogura, T., Takahashi, H., Ohkubo, K., Sudoh, A., Chiyotani, A., Nakachi, I., ... Masugi, Y. (2013). An autopsy case of candidal myocardial abscess in a patient with pneumonia. Japanese Journal of Chest Diseases, 72(6), 670-677.

An autopsy case of candidal myocardial abscess in a patient with pneumonia. / Ogura, Takayuki; Takahashi, Hidenori; Ohkubo, Kosyu; Sudoh, Akihiko; Chiyotani, Atsushi; Nakachi, Ichiro; Kimura, Yoshishige; Tajima, Atsushi; Koh, Hidefumi; Masugi, Yohei.

:: Japanese Journal of Chest Diseases, 巻 72, 番号 6, 2013, p. 670-677.

研究成果: Article

Ogura, T, Takahashi, H, Ohkubo, K, Sudoh, A, Chiyotani, A, Nakachi, I, Kimura, Y, Tajima, A, Koh, H & Masugi, Y 2013, 'An autopsy case of candidal myocardial abscess in a patient with pneumonia', Japanese Journal of Chest Diseases, 巻. 72, 番号 6, pp. 670-677.
Ogura T, Takahashi H, Ohkubo K, Sudoh A, Chiyotani A, Nakachi I その他. An autopsy case of candidal myocardial abscess in a patient with pneumonia. Japanese Journal of Chest Diseases. 2013;72(6):670-677.
Ogura, Takayuki ; Takahashi, Hidenori ; Ohkubo, Kosyu ; Sudoh, Akihiko ; Chiyotani, Atsushi ; Nakachi, Ichiro ; Kimura, Yoshishige ; Tajima, Atsushi ; Koh, Hidefumi ; Masugi, Yohei. / An autopsy case of candidal myocardial abscess in a patient with pneumonia. :: Japanese Journal of Chest Diseases. 2013 ; 巻 72, 番号 6. pp. 670-677.
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AU - Takahashi, Hidenori

AU - Ohkubo, Kosyu

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AU - Chiyotani, Atsushi

AU - Nakachi, Ichiro

AU - Kimura, Yoshishige

AU - Tajima, Atsushi

AU - Koh, Hidefumi

AU - Masugi, Yohei

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AB - A 69-year-old man was admitted to our hospital because of acute respiratory failure and pneumonia. Mechanical ventilation was begun, and antibiotics were subsequently administered. Bronchoalveolar lavage fluid showed fresh blood-like fluid containing hemosiderin-laden macrophages. ANCA and Anti GBM Ab were negative. Finally he was diagnosed with alveolar hemorrhage due to severe pneumonia. After receiving corticosteroid and antibiotics, respiratory failure was improved. One week after extubation, he suddenly developed fever and disturbance of consciousness. Candida albicans was detected from blood and cerebrospinal fluid culture. Despite administration of an antifungal agent, his condition worsened and he died five days after developing fever. Microscopic findings of the autopsy revealed candidal myocardial abscess. We encountered a rare autopsy case of candidal myocardial abscess in non-hematologic disease. This is an important case report to investigate how to diagnose fungal infections and treat them immediately.

KW - Candida albicans

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