抄録
A seven-step and scalable synthesis of dihydronorcapsaicin β-d-glucopyranoside, non-pungent and adrenal secretion enhancement activity (diet effect), was accomplished from vanillin. A simple and inexpensive glucosyl donor, acetobromoglucose, was reacted with phenolic hydroxyl group of α-iodovanillin nitrile under basic conditions. Another key step was the lipase-catalyzed coupling reaction of primary amine, which was resulted from the reduction of the glucosylated product, with methyl nonanoate.
本文言語 | English |
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ページ(範囲) | 197-201 |
ページ数 | 5 |
ジャーナル | Science and Technology of Advanced Materials |
巻 | 7 |
号 | 2 |
DOI | |
出版ステータス | Published - 2006 3 |
ASJC Scopus subject areas
- Materials Science(all)