@article{0f0a6119ab09419896c2dd814bfe1f34,
title = "An inhibitor of the adipogenic differentiation of 3T3-L1 cells, yoshinone A, and its analogs, isolated from the marine cyanobacterium Leptolyngbya sp.",
abstract = "Three novel compounds, yoshinones A, B1, and B2, were isolated from the marine cyanobacterium Leptolyngbya sp., and their structures were elucidated by NMR spectral analysis. Yoshinone A, but not yoshinone B1 or B2, inhibited the differentiation of 3T3-L1 cells into adipocytes. In addition, yoshinone A did not exhibit cytotoxicity, suggesting that yoshinone A may be useful in studies on the treatment of obesity.",
keywords = "3T3-L1 cells, Adipogenesis, Obesity, Yoshinone, γ-Pyrone",
author = "Toshiyasu Inuzuka and Keita Yamamoto and Arihiro Iwasaki and Osamu Ohno and Kiyotake Suenaga and Yoshinori Kawazoe and Daisuke Uemura",
note = "Funding Information: The authors are grateful to Dr. Hiroki Shimogawa for recording the NMR spectra of yoshinones B1 and B2. This study was supported in part by Grant-in-Aid for Scientific Research from JSPS ( 25810096 to T.I., 24310160 to K.S., 24510316 to Y.K., and 25242069 to D.U.) We are indebted to the Uehara Memorial Foundation (D.U.) to financial support. Publisher Copyright: {\textcopyright} 2014 Elsevier Ltd. All rights reserved.",
year = "2014",
month = dec,
day = "3",
doi = "10.1016/j.tetlet.2014.10.032",
language = "English",
volume = "55",
pages = "6711--6714",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "49",
}
