抄録
Background: The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores.Methods: An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients' reports, physicians' records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed.Results: The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients.Conclusions: Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration: Clinical trial registered with UMIN (UMIN000003470).
| 元の言語 | English |
|---|---|
| 記事番号 | 13 |
| ジャーナル | Respiratory Research |
| 巻 | 15 |
| 発行部数 | 1 |
| DOI | |
| 出版物ステータス | Published - 2014 2 6 |
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ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
これを引用
Analysis of comorbid factors that increase the COPD assessment test scores. / Miyazaki, Masaki; Nakamura, Hidetoshi; Chubachi, Shotaro; Sasaki, Mamoru; Haraguchi, Mizuha; Yoshida, Shuichi; Tsuduki, Keishi; Shirahata, Toru; Takahashi, Saeko; Minematsu, Naoto; Koh, Hidefumi; Nakamura, Morio; Sakamaki, Fumio; Terashima, Takeshi; Sayama, Koichi; Jones, Paul W.; Asano, Koichiro; Betsuyaku, Tomoko; Inoue, Takashi; Miyao, Naoki; Nishio, Kazumi; Tateno, Hiroki; Oyamada, Yoshitaka; Matsuzaki, Tatsu; Umeda, Akira.
：: Respiratory Research, 巻 15, 番号 1, 13, 06.02.2014.研究成果: Article
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TY - JOUR
T1 - Analysis of comorbid factors that increase the COPD assessment test scores
AU - Miyazaki, Masaki
AU - Nakamura, Hidetoshi
AU - Chubachi, Shotaro
AU - Sasaki, Mamoru
AU - Haraguchi, Mizuha
AU - Yoshida, Shuichi
AU - Tsuduki, Keishi
AU - Shirahata, Toru
AU - Takahashi, Saeko
AU - Minematsu, Naoto
AU - Koh, Hidefumi
AU - Nakamura, Morio
AU - Sakamaki, Fumio
AU - Terashima, Takeshi
AU - Sayama, Koichi
AU - Jones, Paul W.
AU - Asano, Koichiro
AU - Betsuyaku, Tomoko
AU - Inoue, Takashi
AU - Miyao, Naoki
AU - Nishio, Kazumi
AU - Tateno, Hiroki
AU - Oyamada, Yoshitaka
AU - Matsuzaki, Tatsu
AU - Umeda, Akira
PY - 2014/2/6
Y1 - 2014/2/6
N2 - Background: The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores.Methods: An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients' reports, physicians' records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed.Results: The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients.Conclusions: Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration: Clinical trial registered with UMIN (UMIN000003470).
AB - Background: The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a concise health status measure for COPD. COPD patients have a variety of comorbidities, but little is known about their impact on quality of life. This study was designed to investigate comorbid factors that may contribute to high CAT scores.Methods: An observational study at Keio University and affiliated hospitals enrolled 336 COPD patients and 67 non-COPD subjects. Health status was assessed by the CAT, the St. Georges Respiratory Questionnaire (SGRQ), and all components of the Medical Outcomes Study Short-Form 36-Item (SF-36) version 2, which is a generic measure of health. Comorbidities were identified based on patients' reports, physicians' records, and questionnaires, including the Frequency Scale for the Symptoms of Gastro-esophageal reflux disease (GERD) and the Hospital Anxiety and Depression Scale. Dual X-ray absorptiometry measurements of bone mineral density were performed.Results: The CAT showed moderate-good correlations with the SGRQ and all components of the SF-36. The presence of GERD, depression, arrhythmia, and anxiety was significantly associated with a high CAT score in the COPD patients.Conclusions: Symptomatic COPD patients have a high prevalence of comorbidities. A high CAT score should alert the clinician to a higher likelihood of certain comorbidities such as GERD and depression, because these diseases may co-exist unrecognized. Trial registration: Clinical trial registered with UMIN (UMIN000003470).
KW - Chronic obstructive pulmonary disease
KW - Comorbidity
KW - Depression
KW - Gastro-esophageal reflux
KW - Health status
KW - Osteoporosis
UR - http://www.scopus.com/inward/record.url?scp=84893198662&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84893198662&partnerID=8YFLogxK
U2 - 10.1186/1465-9921-15-13
DO - 10.1186/1465-9921-15-13
M3 - Article
C2 - 24502760
AN - SCOPUS:84893198662
VL - 15
JO - Respiratory Research
JF - Respiratory Research
SN - 1465-9921
IS - 1
M1 - 13
ER -