Angiographic lesion complexity score and in-hospital outcomes after percutaneous coronary intervention

JCD-KICS Investigators

研究成果: Article査読

11 被引用数 (Scopus)

抄録

Objective: We devised a percutaneous coronary intervention (PCI) scoring system based on angio-graphic lesion complexity and assessed its association with in-hospital complications. Background: Although PCI is finding increasing application in patients with coronary artery disease, lesion complexity can lead to in-hospital complications. Methods: Data from 3692 PCI patients were scored based on lesion complexity, defined by bifurcation, chronic total occlusion, type C, and left main lesion, along with acute thrombus in the presence of ST-segment elevation myocardial infarction (1 point assigned for each variable). Results: The patients' mean age was 67.5 +/- 10.8 years; 79.8% were male. About half of the patients (50.3%) presented with an acute coronary syndrome, and 2218 (60.1%) underwent PCI for at least one complex lesion. The patients in the higher-risk score groups were older (p < 0.001) and had present or previous heart failure (p = 0.02 and p = 0.01, respectively). Higher-risk score groups had significantly higher in-hospital event rates for death, heart failure, and cardiogenic shock (from 0 to 4 risk score; 1.7%, 4.5%, 6.3%, 7.1%, 40%, p < 0.001); bleeding with a hemoglobin decrease of >3.0 g/dL (3.1%, 11.0%, 13.1%, 10.3%, 28.6%, p < 0.001); and postoperative myocardial infarction (1.5%, 3.1%, 3.8%, 3.8%, 10%, p = 0.004), respectively. The association with adverse outcomes persisted after adjustment for known clinical predictors (odds ratio 1.72, p < 0.001). Conclusion: The complexity score was cumulatively associated with in-hospital mortality and complication rate and could be used for event prediction in PCI patients.

本文言語English
論文番号e0127217
ジャーナルPloS one
10
6
DOI
出版ステータスPublished - 2015 6月 29

ASJC Scopus subject areas

  • 一般

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