Anodic Oxidation of Phenols: A Key Step for the Synthesis of Natural Products

Takashi Yamamoto, Tsuyoshi Saitoh, Yasuaki Einaga, Shigeru Nishiyama

研究成果: Article査読

3 被引用数 (Scopus)

抄録

Natural products have played a significant role not only in discovery of drugs but also in development of organic chemistry by providing the synthetic challenges. Inspired by biosynthesis where enzymes catalyze a multi-step reaction, we have investigated the natural product synthesis utilizing electrochemical reactions as the key step. Electrochemical organic synthesis, so-called electro-organic synthesis, enables to control the reactivity of substrates simply by tuning electrolysis conditions. In this Personal Account, we overview the recent progress of our research projects about natural product synthesis, in which anodic oxidation of phenol compounds affords the important frameworks such as diaryl ether, spirodienone, and spiroisoxazoline.

本文言語English
ページ(範囲)2254-2268
ページ数15
ジャーナルChemical Record
21
9
DOI
出版ステータスPublished - 2021 9月

ASJC Scopus subject areas

  • 化学 (全般)
  • 生化学
  • 化学工学(全般)
  • 材料化学

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