Anti-colon antibody and lymphocytophilic antibody in ulcerative colitis

T. Hibi, S. Aiso, Tadashi Yoshida, M. Watanabe, H. Asakura, S. Tsuru, M. Tsuchiya

研究成果: Article

30 引用 (Scopus)

抄録

The presence of anti-colon antibody in the sera from patients with ulcerative colitis was demonstrated by antibody-dependent cell-mediated cytotoxicity (ADCC) assay. In addition, the high prevalence of lymphocytophilic antibody in the sera from patients with ulcerative colitis was obtained by fluorescence activated cell sorter (FACS) analysis. This lymphocytophilic antibody was absorbed by rat colon epithelial cells. Moreover the lymphocytes from ulcerative colitis showed lower binding capacity to this antibody, but acquired higher binding capacity after 20 hr incubation at 37°C in vitro. These data suggest that ADCC may have some role in the pathogenesis of ulcerative colitis.

元の言語English
ページ(範囲)75-80
ページ数6
ジャーナルClinical and Experimental Immunology
49
発行部数1
出版物ステータスPublished - 1982

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Ulcerative Colitis
Anti-Idiotypic Antibodies
Colon
Antibody-Dependent Cell Cytotoxicity
Antibodies
Serum
Fluorescence
Epithelial Cells
Lymphocytes

ASJC Scopus subject areas

  • Immunology

これを引用

Hibi, T., Aiso, S., Yoshida, T., Watanabe, M., Asakura, H., Tsuru, S., & Tsuchiya, M. (1982). Anti-colon antibody and lymphocytophilic antibody in ulcerative colitis. Clinical and Experimental Immunology, 49(1), 75-80.

Anti-colon antibody and lymphocytophilic antibody in ulcerative colitis. / Hibi, T.; Aiso, S.; Yoshida, Tadashi; Watanabe, M.; Asakura, H.; Tsuru, S.; Tsuchiya, M.

:: Clinical and Experimental Immunology, 巻 49, 番号 1, 1982, p. 75-80.

研究成果: Article

Hibi, T, Aiso, S, Yoshida, T, Watanabe, M, Asakura, H, Tsuru, S & Tsuchiya, M 1982, 'Anti-colon antibody and lymphocytophilic antibody in ulcerative colitis', Clinical and Experimental Immunology, 巻. 49, 番号 1, pp. 75-80.
Hibi T, Aiso S, Yoshida T, Watanabe M, Asakura H, Tsuru S その他. Anti-colon antibody and lymphocytophilic antibody in ulcerative colitis. Clinical and Experimental Immunology. 1982;49(1):75-80.
Hibi, T. ; Aiso, S. ; Yoshida, Tadashi ; Watanabe, M. ; Asakura, H. ; Tsuru, S. ; Tsuchiya, M. / Anti-colon antibody and lymphocytophilic antibody in ulcerative colitis. :: Clinical and Experimental Immunology. 1982 ; 巻 49, 番号 1. pp. 75-80.
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