Application of Hydrogel Microspheres to Latex Diagnosis

Taro Akazawa, Keiji Fujimoto, Haruma Kawaguchi

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Acrylamide, glycidyl methacrylate, and methylene bisacrylamide were copolymerized in an aqueous ethanol to form monodisperse hydrogel latex particles. Antibody of C-reactive protein (CRP) was immobilized on the particles through a hydrophilic spacer. The resulting particles were moderately stable, and the agglutination was proportional to the concentration of CRP. They were little susceptible to the nonspecific adsorption of proteins and the aggregation by rheumatoid factor. Therefore, it was concluded that the hydrogel particles are a promising carrier of antibodies for latex diagnosis.

本文言語English
ページ(範囲)431-435
ページ数5
ジャーナルKOBUNSHI RONBUNSHU
50
5
DOI
出版ステータスPublished - 1993

ASJC Scopus subject areas

  • 化学工学(その他)
  • 材料科学(その他)
  • 環境科学(全般)
  • ポリマーおよびプラスチック

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