AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression

Medicine & Life Sciences

• Aquaporins 100%
• Colonic Neoplasms 70%
• Lactic Acid 69%
• Macrophages 54%
• Neoplasms 25%
• Tumor Microenvironment 24%
• Vascular Endothelial Growth Factor A 13%
• Cricetulus 8%
• Glycerol 8%
• Knockout Mice 7%
• Allografts 6%
• Ovary 6%
• Water 5%
• Carcinoma 5%
• Neoplasm Metastasis 4%
• Growth 3%

Chemical Compounds

• Lactate 78%
• Polarization 57%
• Glycerol 11%
• Metabolite 9%