Assessment of mitophagy in iPS cell-derived neurons

Kei Ichi Ishikawa, Akihiro Yamaguchi, Hideyuki Okano, Wado Akamatsu

研究成果: Chapter

2 引用 (Scopus)

抄録

Aberrant mitochondrial function is associated with many neurological diseases. Mitophagy is a key mechanism for the elimination of damaged mitochondria and maintenance of mitochondrial homeostasis. Induced pluripotent stem (iPS) cell technologies developed over the last decade have allowed us to analyze functions of the human neuron. Here we describe an efficient induction method from human iPS cells to neurons, followed by an image-based mitophagy assay.

元の言語English
ホスト出版物のタイトルMethods in Molecular Biology
出版者Humana Press Inc.
ページ59-67
ページ数9
DOI
出版物ステータスPublished - 2018 1 1

出版物シリーズ

名前Methods in Molecular Biology
1759
ISSN(印刷物)1064-3745

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Mitochondrial Degradation
Induced Pluripotent Stem Cells
Neurons
Mitochondria
Homeostasis
Maintenance
Technology

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

これを引用

Ishikawa, K. I., Yamaguchi, A., Okano, H., & Akamatsu, W. (2018). Assessment of mitophagy in iPS cell-derived neurons. : Methods in Molecular Biology (pp. 59-67). (Methods in Molecular Biology; 巻数 1759). Humana Press Inc.. https://doi.org/10.1007/7651_2017_10

Assessment of mitophagy in iPS cell-derived neurons. / Ishikawa, Kei Ichi; Yamaguchi, Akihiro; Okano, Hideyuki; Akamatsu, Wado.

Methods in Molecular Biology. Humana Press Inc., 2018. p. 59-67 (Methods in Molecular Biology; 巻 1759).

研究成果: Chapter

Ishikawa, KI, Yamaguchi, A, Okano, H & Akamatsu, W 2018, Assessment of mitophagy in iPS cell-derived neurons. : Methods in Molecular Biology. Methods in Molecular Biology, 巻. 1759, Humana Press Inc., pp. 59-67. https://doi.org/10.1007/7651_2017_10
Ishikawa KI, Yamaguchi A, Okano H, Akamatsu W. Assessment of mitophagy in iPS cell-derived neurons. : Methods in Molecular Biology. Humana Press Inc. 2018. p. 59-67. (Methods in Molecular Biology). https://doi.org/10.1007/7651_2017_10
Ishikawa, Kei Ichi ; Yamaguchi, Akihiro ; Okano, Hideyuki ; Akamatsu, Wado. / Assessment of mitophagy in iPS cell-derived neurons. Methods in Molecular Biology. Humana Press Inc., 2018. pp. 59-67 (Methods in Molecular Biology).
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