Assessment of mitophagy in iPS cell-derived neurons

Kei Ichi Ishikawa, Akihiro Yamaguchi, Hideyuki Okano, Wado Akamatsu

研究成果: Chapter

2 引用 (Scopus)

抜粋

Aberrant mitochondrial function is associated with many neurological diseases. Mitophagy is a key mechanism for the elimination of damaged mitochondria and maintenance of mitochondrial homeostasis. Induced pluripotent stem (iPS) cell technologies developed over the last decade have allowed us to analyze functions of the human neuron. Here we describe an efficient induction method from human iPS cells to neurons, followed by an image-based mitophagy assay.

元の言語English
ホスト出版物のタイトルMethods in Molecular Biology
出版者Humana Press Inc.
ページ59-67
ページ数9
DOI
出版物ステータスPublished - 2018 1 1

出版物シリーズ

名前Methods in Molecular Biology
1759
ISSN(印刷物)1064-3745

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

フィンガープリント Assessment of mitophagy in iPS cell-derived neurons' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Ishikawa, K. I., Yamaguchi, A., Okano, H., & Akamatsu, W. (2018). Assessment of mitophagy in iPS cell-derived neurons. : Methods in Molecular Biology (pp. 59-67). (Methods in Molecular Biology; 巻数 1759). Humana Press Inc.. https://doi.org/10.1007/7651_2017_10