Association of calcineurin A gamma subunit (PPP3CC) and early growth response 3 (EGR3) gene polymorphisms with susceptibility to schizophrenia in a Japanese population

Chieko Kyogoku, Masaya Yanagi, Kunihiro Nishimura, Daisuke Sugiyama, Akio Morinobu, Masaaki Fukutake, Kiyoshi Maeda, Osamu Shirakawa, Takayoshi Kuno, Shunichi Kumagai

研究成果: Article査読

16 被引用数 (Scopus)

抄録

To examine the association of PPP3CC (rs10108011 and rs2461491) and EGR3 (rs3750192) single-nucleotide polymorphisms (SNPs) with Japanese schizophrenia, we performed a case-control association study using 337 patients and 369 healthy controls. As a result, by our moderated cohort-size study, PPP3CC and EGR3 are not genetic risk factors for schizophrenia, whereas meta-analysis showed weak association of rs10108011 with schizophrenia in the Japanese population (odds ratio (OR) = 1.12, P= 0.01).

本文言語English
ページ(範囲)16-19
ページ数4
ジャーナルPsychiatry Research
185
1-2
DOI
出版ステータスPublished - 2011 1 30
外部発表はい

ASJC Scopus subject areas

  • 精神医学および精神衛生
  • 生物学的精神医学

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