Association of ras p21 with differentiation of epidermal keratinocytes in proliferating skin diseases

Arata Kikuchi, Masayuki Amagai, Takeji Nishikawa

研究成果: Article査読

3 被引用数 (Scopus)

抄録

We examined the localization of DNA replicating cells and ras oncogene product p21 positive cells in proliferating skin diseases, such as psoriasis vulgaris, lichen planus, verruca vulgaris, verruca plana juvenilis and seborrheic keratosis. ras p21-positive cells were found rather in the differentiated layers than in the proliferating layers of the epidermis. We indicate that the expression of ras p21 can be associated with the differentiation of epidermal keratinocytes not only in tumor tissues but also in inflammatory skin diseases.

本文言語English
ページ(範囲)83-86
ページ数4
ジャーナルJournal of Dermatological Science
4
2
DOI
出版ステータスPublished - 1992 9月

ASJC Scopus subject areas

  • 生化学
  • 分子生物学
  • 皮膚病学

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