Asymmetric decarboxylation of disubstituted malonic acid by alcaligenes bronchisepticus KU 1201

Kenji Miyamoto, Hiromichi Ohta

研究成果: Article査読

41 被引用数 (Scopus)

抄録

Optically active αarylpropionic acids constitute a group which involves many useful compounds. We selected a microorganism which has the ability to realize the asymmetric decarboxylation of αmethyl-αphenylmalonic acid to afford optically active αphenylpropionic acid and it identified as Alcaligenes bronchisepticus KU 1201. When the aryl group was phenyl, 4-chlorophenyl, 6-methoxy-2-naphthyl or 2-thienyl, the substrate afforded optically active αarylpropionic acid in high optical and chemical yield.

本文言語English
ページ(範囲)49-60
ページ数12
ジャーナルBiocatalysis and Biotransformation
5
1
DOI
出版ステータスPublished - 1991

ASJC Scopus subject areas

  • Biotechnology
  • Catalysis
  • Biochemistry

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