Asymmetric hydrolysis of l-Cyanoalkyl acetates

Hiromichi Ohta, Satoshi Hiraga, Kenji Miyamoto, Gen Ichi Tsuchihashi

研究成果: Article査読

20 被引用数 (Scopus)

抄録

Microorganisms that enantioselectively hydrolyze I-cyanoalkyl acetates (aldehyde cyanohydrin) were screened. Candida tropicalis was found to be the best. The enzyme system of this strain catalyzed the enantioselective hydrolysis of (S)-isomers, leaving behind the (R)-acetates. The optical purities of recovered acetates were high as measured by IH-NMR analysis in the presence of a chiral shift reagent.

本文言語English
ページ(範囲)3023-3027
ページ数5
ジャーナルAgricultural and biological chemistry
52
12
DOI
出版ステータスPublished - 1988 12

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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