Asymmetric induction in cyclohexadienones carrying α-D-glucopyranosyl moiety

Saki Yajima, Tsuyoshi Saitoh, Kohei Kawa, Kensuke Nakamura, Hiroshi Nagase, Yasuaki Einaga, Shigeru Nishiyama

研究成果: Article査読

5 被引用数 (Scopus)

抄録

Cyclohexadienone derivatives possessing α-D-glucopyranosyl moiety were designed and synthesized using chemical oxidation or electrochemical oxidation with boron-doped diamond electrode in the final stage. In the chiral induction studies, catalytic hydrogenation provided high diastereoselectivity (dr ratio: > 9:1). Conformational analyses of the C-glucoside structures were performed by NOE experiments and force field calculations, and supported the observed regio-selectivity.

本文言語English
ページ(範囲)8428-8435
ページ数8
ジャーナルTetrahedron
72
51
DOI
出版ステータスPublished - 2016

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

フィンガープリント 「Asymmetric induction in cyclohexadienones carrying α-D-glucopyranosyl moiety」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル