抄録
There have been many clinical and scientific advancements since the first clinical case using cultured keratinocytes was performed in 1981. Autologous cultured keratinocytes are applied for the permanent coverage of wounds. In contrast, the allogeneic type is thought to be an ideal biological dressing due to the stimulating epithelialization from the remnant skin appendage and wound margin. This paper focuses on the autologous type and describes our clinical experiences, including four cases: a third-degree burn, a giant nevus, a vitiligo, and a meshed skin graft scar. From 1985, we have treated the following diseases with autologous cultured keratinocytes and have had satisfactory results: I) Full thickness skin defect: Third- degree burn, giant nevus - Allogeneic skin graft is performed before autologous cultured keratinocyte grafting (Cuono's method) - II) Skin color disorder: Vitiligo, pigmentation or depigmentation after conventional skin grafting - III) Skin surface irregularity: Burn scar, meshed skin graft scar - Autologous cultured keratinocyte grafts are well known as a useful procedure for massive burns. Furthermore, they are also beneficial for the treatment of various kinds of disfigurements in plastic surgery.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 533-540 |
| ページ数 | 8 |
| ジャーナル | Japanese Journal of Plastic and Reconstructive Surgery |
| 巻 | 43 |
| 発行部数 | 6 |
| 出版物ステータス | Published - 2000 |
| 外部発表 | Yes |
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ASJC Scopus subject areas
- Surgery
これを引用
Autologous cultured keratinocytes : Significance in plastic surgery. / Matsuzaki, K.; Kumagai, N.
：: Japanese Journal of Plastic and Reconstructive Surgery, 巻 43, 番号 6, 2000, p. 533-540.研究成果: Article
}
TY - JOUR
T1 - Autologous cultured keratinocytes
T2 - Significance in plastic surgery
AU - Matsuzaki, K.
AU - Kumagai, N.
PY - 2000
Y1 - 2000
N2 - There have been many clinical and scientific advancements since the first clinical case using cultured keratinocytes was performed in 1981. Autologous cultured keratinocytes are applied for the permanent coverage of wounds. In contrast, the allogeneic type is thought to be an ideal biological dressing due to the stimulating epithelialization from the remnant skin appendage and wound margin. This paper focuses on the autologous type and describes our clinical experiences, including four cases: a third-degree burn, a giant nevus, a vitiligo, and a meshed skin graft scar. From 1985, we have treated the following diseases with autologous cultured keratinocytes and have had satisfactory results: I) Full thickness skin defect: Third- degree burn, giant nevus - Allogeneic skin graft is performed before autologous cultured keratinocyte grafting (Cuono's method) - II) Skin color disorder: Vitiligo, pigmentation or depigmentation after conventional skin grafting - III) Skin surface irregularity: Burn scar, meshed skin graft scar - Autologous cultured keratinocyte grafts are well known as a useful procedure for massive burns. Furthermore, they are also beneficial for the treatment of various kinds of disfigurements in plastic surgery.
AB - There have been many clinical and scientific advancements since the first clinical case using cultured keratinocytes was performed in 1981. Autologous cultured keratinocytes are applied for the permanent coverage of wounds. In contrast, the allogeneic type is thought to be an ideal biological dressing due to the stimulating epithelialization from the remnant skin appendage and wound margin. This paper focuses on the autologous type and describes our clinical experiences, including four cases: a third-degree burn, a giant nevus, a vitiligo, and a meshed skin graft scar. From 1985, we have treated the following diseases with autologous cultured keratinocytes and have had satisfactory results: I) Full thickness skin defect: Third- degree burn, giant nevus - Allogeneic skin graft is performed before autologous cultured keratinocyte grafting (Cuono's method) - II) Skin color disorder: Vitiligo, pigmentation or depigmentation after conventional skin grafting - III) Skin surface irregularity: Burn scar, meshed skin graft scar - Autologous cultured keratinocyte grafts are well known as a useful procedure for massive burns. Furthermore, they are also beneficial for the treatment of various kinds of disfigurements in plastic surgery.
UR - http://www.scopus.com/inward/record.url?scp=0033939044&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033939044&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0033939044
VL - 43
SP - 533
EP - 540
JO - Japanese Journal of Plastic Surgery
JF - Japanese Journal of Plastic Surgery
SN - 0021-5228
IS - 6
ER -