Backbone resonance assignments for the cytoplasmic regions of G protein-activated inwardly rectifying potassium channel 1 (GIRK1)

Mariko Yokogawa, Takahiro Muramatsu, Koh Takeuchi, Masanori Osawa, Ichio Shimada

研究成果: Article査読

5 被引用数 (Scopus)

抄録

G protein-activated inwardly rectifying potassium channel (GIRK) plays crucial roles in regulating heart rate and neuronal excitability in eukaryotic cells. A variety of ligands, including heterotrimeric G protein βγ subunits (Gβγ), bind to the cytoplasmic regions of GIRK and modulate its activity. We established the backbone resonance assignments of 2H/13C/15N-labeled cytoplasmic regions of mouse GIRK1, which form a tetramer with a molecular weight of 96 K.

本文言語English
ページ(範囲)125-128
ページ数4
ジャーナルBiomolecular NMR Assignments
3
1
DOI
出版ステータスPublished - 2009 6月
外部発表はい

ASJC Scopus subject areas

  • 構造生物学
  • 生化学

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