Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection

Tatsuya Nishihara, Satoshi Kuno, Hiroshi Nonaka, Sho Tabata, Natsumi Saito, Shinji Fukuda, Masaru Tomita, Shinsuke Sando, Tomoyoshi Soga

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Tumor biomarkers are highly desirable for the screening of patients with a risk of tumor development and progression. Here, we report a beta-galactosidase (β-gal)-responsive acetaminophen (β-GR-APAP) as a synthetic plasma biomarker for targeted tumor detection. Tumor β-gal labeling via the recognition of tumor-related antigen enabled the detection of a tumor using β-GR-APAP.

本文言語English
ページ(範囲)11745-11748
ページ数4
ジャーナルChemical Communications
54
83
DOI
出版ステータスPublished - 2018

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

フィンガープリント 「Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル