抄録
This review covers recent examples of synthetic transformation of nitriles and amides by microbial enzyme systems. A variety of substrates and products involving enantiomerically enriched forms of chiral substances are referred to. The stereochemical course of enzyme-catalyzed hydrolysis is briefly commented on. Special emphasis is placed upon the range of functional groups that are acceptable by enzymes and/or survive under the transformation, as well as the advantages as a synthetic tool for conversion under mild conditions.
本文言語 | English |
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ページ(範囲) | 1419-1427 |
ページ数 | 9 |
ジャーナル | Bioscience, Biotechnology and Biochemistry |
巻 | 61 |
号 | 9 |
DOI | |
出版ステータス | Published - 1997 1 |
ASJC Scopus subject areas
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry