抄録
The scope and limitation of a bottom-fermentation yeast (Saccharomyces cerevisiae IFO 0565) toward the reduction of 3-oxoalkanoic esters were examined. The substrate specificity of this microorganism for various kinds of 3-oxoalkanoic esters was studied. This microorganism was distinct from converntional bakers’ yeast in terms of its selectivity in the reduction and its high expression of a hydrolytic enzyme. 3-Oxoalkanoic ester with an aromatic substituent, a halogen substituted 3-oxoalkanoic ester, an aliphatic longer-chain 3-oxoalkanoic ester and its α, αα-difluoro analog were also accepted by this microorganism. The products are useful intermediates in the synthesis of physiologically active compounds.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 1666-1670 |
| ページ数 | 5 |
| ジャーナル | Bioscience, Biotechnology, and Biochemistry |
| 巻 | 58 |
| 号 | 9 |
| DOI | |
| 出版ステータス | Published - 1994 |
ASJC Scopus subject areas
- バイオテクノロジー
- 分析化学
- 生化学
- 応用微生物学とバイオテクノロジー
- 分子生物学
- 有機化学