Biochemistry and metabolism of toxoplasma gondii

T. Asai, S. Tomavo

研究成果: Chapter

3 被引用数 (Scopus)

抄録

Toxoplasma gondii and all other parasites of the phylum Apicomplexa reside and replicate exclusively within eukaryotic cells. It suggests that these parasites depend on the metabolism of their hosts and that they have evolved metabolic pathways reflecting their intracellular lifestyle. In addition, these parasites may display specific or alternate metabolism as documented by the recent discovery of novel metabolic pathways in the remnant and vestigial plastid (apicoplast) found in many apicomplexan parasites. While targeting unique parasite pathways is an attractive strategy, in practice the procurement of enough pure parasites for biochemical study or purification of parasite components such as enzymes is extremely difficult. Biochemical and metabolic studies of T. gondii have also been difficult to execute because of continual problems with contamination of parasite preparations with host-cell components. © 2007

本文言語English
ホスト出版物のタイトルToxoplasma Gondii
出版社Elsevier Ltd
ページ185-206
ページ数22
ISBN(印刷版)9780123695420
DOI
出版ステータスPublished - 2007

ASJC Scopus subject areas

  • 農業および生物科学(全般)

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