TY - JOUR
T1 - Biodegradation of PET
T2 - Current Status and Application Aspects
AU - Taniguchi, Ikuo
AU - Yoshida, Shosuke
AU - Hiraga, Kazumi
AU - Miyamoto, Kenji
AU - Kimura, Yoshiharu
AU - Oda, Kohei
N1 - Funding Information:
We acknowledge fruitful discussions with T. Takehana, H. Yamaji, Y. Maeda, and K. Toyohara. We thank A. Wlodawer for comments on this manuscript. This work was supported by a JSPS KAKENHI Grant-in-Aid for Scientific Research (B) (17H03794 to S.Y.) and a JSPS KAKENHI Grant-in-Aid for Scientific Research (A) (JP18H03857 to K.M.).
Publisher Copyright:
© 2019 American Chemical Society.
PY - 2019/5/3
Y1 - 2019/5/3
N2 - Most petroleum-derived plastics, as exemplified by poly(ethylene terephthalate) (PET), are chemically inactive and highly resistant to microbial attack. The accumulation of plastic waste results in environmental pollution and threatens ecosystems, referred to as the "microplastic issue". Recently, PET hydrolytic enzymes (PHEs) have been identified and we reported PET degradation by a microbial consortium and its bacterial resident, Ideonella sakaiensis. Bioremediation may thus provide an alternative solution to recycling plastic waste. The mechanism of PET degradation into benign monomers by PET hydrolase and mono(2-hydroxyethyl) terephthalic acid (MHET) hydrolase from I. sakaiensis has been elucidated; nevertheless, biodegradation may require additional development for commercialization owing to the low catalytic activity of these enzymes. Here, we introduce PET degrading microorganisms and the enzymes involved, along with the evolution of PHEs to address the issues that hamper microbial and enzymatic PET degradation. Potential applications of PET degradation are also discussed.
AB - Most petroleum-derived plastics, as exemplified by poly(ethylene terephthalate) (PET), are chemically inactive and highly resistant to microbial attack. The accumulation of plastic waste results in environmental pollution and threatens ecosystems, referred to as the "microplastic issue". Recently, PET hydrolytic enzymes (PHEs) have been identified and we reported PET degradation by a microbial consortium and its bacterial resident, Ideonella sakaiensis. Bioremediation may thus provide an alternative solution to recycling plastic waste. The mechanism of PET degradation into benign monomers by PET hydrolase and mono(2-hydroxyethyl) terephthalic acid (MHET) hydrolase from I. sakaiensis has been elucidated; nevertheless, biodegradation may require additional development for commercialization owing to the low catalytic activity of these enzymes. Here, we introduce PET degrading microorganisms and the enzymes involved, along with the evolution of PHEs to address the issues that hamper microbial and enzymatic PET degradation. Potential applications of PET degradation are also discussed.
KW - Ideonella sakaiensis
KW - PET hydrolase (PETase)
KW - PET hydrolytic enzyme (PHE)
KW - microbial consortium
KW - mono(2-hydroxyethyl) terephthalic acid hydrolase (MHETase)
KW - poly(ethylene terephthalate) (PET)
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U2 - 10.1021/acscatal.8b05171
DO - 10.1021/acscatal.8b05171
M3 - Article
AN - SCOPUS:85064825065
SN - 2155-5435
VL - 9
SP - 4089
EP - 4105
JO - ACS Catalysis
JF - ACS Catalysis
IS - 5
ER -
