Biofabrication of pseudocardiac tublar tissues with gel fibers including rat cardiomyocytes

Shintaroh Iwanaga, Hiroaki Onoe, Shoji Takeuchi

研究成果: Conference contribution

抄録

This paper describes a tissue-fabrication method utilizing with 'cell fiber': a core-shell hydrogel fiber encapsulating cells in the core. We use coaxial microfluidic channels to fabricate collagen/alginate or fibrin/alginate core-shell fibers. Rat primary cardiomyocytes were well cultured within the fibrin-based cell fiber, successfully contracting with the alginate shell. By twisting up cardio-fibers, we can easily prepare coiled tublar tissues. This approach would be applicable for the rapid biofabrication of large-scaled 3D tissues.

本文言語English
ホスト出版物のタイトル15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
ページ861-863
ページ数3
出版ステータスPublished - 2011 12 1
外部発表はい
イベント15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
継続期間: 2011 10 22011 10 6

出版物シリーズ

名前15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
2

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period11/10/211/10/6

ASJC Scopus subject areas

  • Control and Systems Engineering

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