Biohybrid neural probe: A neural probe having cultured neurons between an electrode and tissue

Keisuke Okita, Midori Kato-Negishi, Hiroaki Onoe, Riho Gojo, Tetsuhiko Teshima, Shoji Takeuchi

研究成果: Conference contribution

2 被引用数 (Scopus)

抄録

We propose a neural probe combined with a neuronal spheroid (neurospheroid) cultured on electrodes for deep brain stimulation. Since neurons of the spheroid extend their axons deep into the brain tissue, the neural probe can electrically stimulate deep brain area via the neurons without inserting an invasive probe. Here we first fabricated an electrode and then successfully placed a neurospheorid at the electrodes tip, named a "biohybrid neural probe". Furthermore, we tried to make the fabricated probe contact with cultured cortical cells on glass. We believe that our biohybrid neural probe has a potential to provide minimally invasive stimulation to the brain tissue.

本文言語English
ホスト出版物のタイトル15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
ページ332-334
ページ数3
出版ステータスPublished - 2011 12 1
外部発表はい
イベント15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
継続期間: 2011 10 22011 10 6

出版物シリーズ

名前15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
1

Other

Other15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period11/10/211/10/6

ASJC Scopus subject areas

  • Control and Systems Engineering

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