Biselyngbyolide B, a novel ER stress-inducer isolated from the marine cyanobacterium Lyngbya sp.

Osamu Ohno, Ayane Watanabe, Maho Morita, Kiyotake Suenaga

研究成果: Article査読

21 被引用数 (Scopus)

抄録

A novel cytotoxic macrolide biselyngbyolide B (1) was isolated from the marine cyanobacterium Lyngbya sp., collected on Ishigaki Island, Japan. The structure of 1 was determined to be the aglycone of biselyngbyaside (2) on the basis of 1D and 2DNMR spectra and CD data. The apoptosis-inducing activity of 1 was 30- to 100-fold greater than that of 2. In addition, 1 was found to exhibit ER stress-inducing activity.

本文言語English
ページ(範囲)287-289
ページ数3
ジャーナルChemistry Letters
43
3
DOI
出版ステータスPublished - 2014

ASJC Scopus subject areas

  • 化学 (全般)

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