Camptocormia in Japanese patients with Parkinson's disease: A multicenter study

Morinobu Seki, Kazushi Takahashi, Atsuo Koto, Ban Mihara, Yoko Morita, Kazuo Isozumi, Kouichi Ohta, Kazuhiro Muramatsu, Jun Gotoh, Keiji Yamaguchi, Yutaka Tomita, Hideki Sato, Yoshihiro Nihei, Satoko Iwasawa, Norihiro Suzuki

研究成果: Article査読

32 被引用数 (Scopus)

抄録

Objective: The aim of this work was to investigate the prevalence of camptocormia and the clinical characteristics of patients with camptocormia in a large population of PD patients. Background: Although camptocormia has been recognized as a prominent phenomenon in PD, the previous epidemiological reports were limited, especially in terms of sample size. Methods:: We evaluated 531 PD patients (disease duration: 7.0 ± 5.5 years, mean ± standard deviation). We examined their clinical features and the prevalence of camptocormia. Results: Camptocormia was detected in 22 patients (4.1%) and found in patients who were older and had more severe motor symptoms and a higher levodopa (L-dopa) dose (P < 0.05), compared to the patients without camptocormia. Patients with camptocormia showed significantly higher frequencies of autonomic symptoms, such as constipation and urinary incontinence (P < 0.05). Conclusions: Camptocormia is uncommon in PD and is associated with disease severity, higher L-dopa dose and higher frequencies of autonomic symptoms.

本文言語English
ページ(範囲)2567-2571
ページ数5
ジャーナルMovement Disorders
26
14
DOI
出版ステータスPublished - 2011 12

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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