Can we harness the microbiota to enhance the efficacy of cancer immunotherapy?

B. Brett Finlay, Romina Goldszmid, Kenya Honda, Giorgio Trinchieri, Jennifer Wargo, Laurence Zitvogel

研究成果: Article査読

2 被引用数 (Scopus)

抄録

There is currently much interest in defining how the microbiota shapes immune responses in the context of cancer. Various studies in both mice and humans have associated particular commensal species with better (or worse) outcomes in different cancer types and following treatment with cancer immunotherapies. However, the mechanisms involved remain ill-defined and even controversial. In this Viewpoint, Nature Reviews Immunology has invited six eminent scientists in the field to share their thoughts on the key questions and challenges for the field.

本文言語English
ページ(範囲)522-528
ページ数7
ジャーナルNature Reviews Immunology
20
9
DOI
出版ステータスPublished - 2020 9 1

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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