Candidate biomarkers for genetic and clinic opathological diagnosis of endometrial cancer

Kouji Banno, Yuya Nogami, Iori Kisu, Megumi Yanokura, Kiyoko Umene, Kenta Masuda, Yusuke Kobayashi, Wataru Yamagami, Nobuyuki Susumu, Daisuke Aoki

研究成果: Review article査読

16 被引用数 (Scopus)

抄録

The recent increase in the frequency of endometrial cancer has emphasized the need for accurate diagnosis and improved treatment. The current diagnosis is still based on conventional pathological indicators, such as clinical stage, tumor differentiation, invasion depth and vascular invasion. However, the genetic mechanisms underlying endometrial cancer have gradually been determined, due to developments in molecular biology, leading to the possibility of new methods of diagnosis and treatment planning. New candidate biomarkers for endometrial cancer include those for molecular epigenetic mutations, such as microRNAs. These biomarkers may permit earlier detection of endometrial cancer and prediction of outcomes and are likely to contribute to future personalized therapy for endometrial cancer.

本文言語English
ページ(範囲)12123-12137
ページ数15
ジャーナルInternational journal of molecular sciences
14
6
DOI
出版ステータスPublished - 2013 6月

ASJC Scopus subject areas

  • 触媒
  • 分子生物学
  • 分光学
  • コンピュータ サイエンスの応用
  • 物理化学および理論化学
  • 有機化学
  • 無機化学

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