Carbohydrate-modulated DNA photocleavage: Design, synthesis, and evaluation of novel glycosyl anthraquinones

Kazunobu Toshima, Yutaka Maeda, Hiromi Ouchi, Akira Asai, Shuichi Matsumura

研究成果: Article査読

33 被引用数 (Scopus)

抄録

Novel and artificial anthraquinone-carbohydrate hybrids were designed and synthesized, and found to effectively cleave DNA under irradiation with a long wavelength UV light and also exhibit cytotoxicity against HeLa S3 cells. (C) 2000 Elsevier Science Ltd.

本文言語English
ページ(範囲)2163-2165
ページ数3
ジャーナルBioorganic and Medicinal Chemistry Letters
10
19
DOI
出版ステータスPublished - 2000 10 2

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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