Catalytic atropo-enantioselective reduction of biaryl lactones to axially chiral biaryl compounds

Tomoko Ashizawa, Saiko Tanaka, Tohru Yamada

研究成果: Article査読

47 被引用数 (Scopus)

抄録

(Chemical Equation Presented) The atropo-enantioselective borohydride reduction with dynamic kinetic resolution of biaryl lactones was catalyzed by an optically active β-ketoiminatocobalt(II) complex to afford optically active biaryl compounds. Chiral HPLC analysis of the starting biaryl lactones was performed at various temperatures to determine suitable reaction conditions for dynamic kinetic resolution. Various types of axially chiral biaryl compounds were obtained with high enantioselectivity.

本文言語English
ページ(範囲)2521-2524
ページ数4
ジャーナルOrganic Letters
10
12
DOI
出版ステータスPublished - 2008 12 1

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

フィンガープリント

「Catalytic atropo-enantioselective reduction of biaryl lactones to axially chiral biaryl compounds」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル