Catalytic enantioselective addition of diethyl phosphite to N-thiophosphinoyl ketimines: Preparation of (R)-diethyl (1-amino-1-phenylethyl)phosphonate

Shaoquan Lin, Yasunari Otsuka, Liang Yin, Naoya Kumagai, Masakatsu Shibasaki

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Procedures yielding phosphinothioic amide 2 and ketimine 4 as colorless crystals and phosphonate 6 as a brown viscous oil are presented. Notes on instruments and chemicals required are provided.A brief discussion on construction of tetrasubstituted stereogenic centers in a catalytic and enantioselective manner as a significant progress in asymmetric catalysis.

本文言語English
ジャーナルOrganic Syntheses
94
DOI
出版ステータスPublished - 2018 6 20
外部発表はい

ASJC Scopus subject areas

  • 物理化学および理論化学
  • 有機化学

フィンガープリント

「Catalytic enantioselective addition of diethyl phosphite to N-thiophosphinoyl ketimines: Preparation of (R)-diethyl (1-amino-1-phenylethyl)phosphonate」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル