@article{5ad5a08e10fd41b18bfb24f4581d0765,
title = "CD36 single nucleotide polymorphism is associated with variation in low-density lipoprotein-cholesterol in young Japanese men",
abstract = "Macrophages uptake oxidized low-density lipoprotein (LDL) via a scavenger receptor such as CD36 from plasma, and then become foam cells. We examined the association of CD36 gene single nucleotide polymorphisms (SNPs) with certain metabolic characteristics in a young male Japanese population (n494). The G allele in a SNP located at 30215 on the 3'-untranslated region (UTR) was significantly orrelated with the plasma LDL-cholesterol concentrations (r=0.13, p<0.01). The difference in LDL-cholesterol concentrations was 10mg dl -1 between GG- and AA-genotype carriers (p<0.05). The CD36 gene SNP is a novel maker of the variation in the LDL-cholesterol levels in young Japanese men.",
keywords = "CD36, LDL-cholesterol, Single nucleotide polymorphism",
author = "Toshiyuki Morii and Yoichi Ohno and Norihiro Kato and Hiroshi Hirose and Hiroshi Kawabe and Keiichi Hirao and Takashi Eguchi and Tatsuya Maruyama and Matsuhiko Hayashi and Ikuo Saito and Yoshio Yazaki and Takao Saruta",
note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research on Priority Areas (C) Medical Genome Science from the Ministry of Education, Culture, Sports, Science and Technology of Japan. We thank all the study participants who contributed their DNA for making this study possible. We also thank Hirokazu Sakai for help with DNA analysis.",
year = "2009",
month = jun,
doi = "10.1080/13547500902811274",
language = "English",
volume = "14",
pages = "207--212",
journal = "Biomarkers",
issn = "1354-750X",
publisher = "Informa Healthcare",
number = "4",
}