Cell manipulation by nodal circle resonance vibration of a cell cultivation substrate

Chikahiro Imashiro, Yuta Kurashina, Kenjiro Takemura, Shogo Miyata, Jun Komotori

研究成果: Conference contribution

1 被引用数 (Scopus)

抄録

In this paper, we propose a novel cell culture method to generate an organ without scaffold. The concept of our study is to apply the principle of Chladni's figures in cell manipulation. To confirm this concept, we developed cell cultivation device that can excite resonance vibration of the cell cultivation substrate. After the fabrication of the device, we estimated the resonance frequency and vibration amplitude distribution of our device. Since the fabricated device successfully produced the designed vibration mode, we conducted cell manipulation experiment to confirm our concept. In our experiment, we varied the initial number of cells that were seeded into our device. Cells were manipulated by resonance vibration for 120 min. After the manipulation, we checked cell distribution on the substrate. As a result, cells were successfully manipulated by the resonance vibration when the initial number of cells was appropriate.

本文言語English
ホスト出版物のタイトル2015 IEEE International Ultrasonics Symposium, IUS 2015
出版社Institute of Electrical and Electronics Engineers Inc.
ISBN(印刷版)9781479981823
DOI
出版ステータスPublished - 2015 11 13
イベントIEEE International Ultrasonics Symposium, IUS 2015 - Taipei, Taiwan, Province of China
継続期間: 2015 10 212015 10 24

Other

OtherIEEE International Ultrasonics Symposium, IUS 2015
国/地域Taiwan, Province of China
CityTaipei
Period15/10/2115/10/24

ASJC Scopus subject areas

  • 音響学および超音波学

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