TY - GEN
T1 - Cell segmentation from phase-contrast images using hybrid watershed and region growing algorithm for genomic drug discovery
AU - Orikawa, Jo
AU - Tanaka, Toshiyuki
PY - 2010/1/1
Y1 - 2010/1/1
N2 - Currently the existing computer analysis system for genomic drug discovery does not take it in to account that when cells are examined microscopically, excitation light or phosphor that is used on this occasion affects them adversely. We focused attention on phase microscope which can observe cells noninvasively. Until now, phase-contrast image has been difficult to process because recognition rate varies according to conditions, and for this, appropriate analyzing system has not been established. The study succeeded location of almost all cells. Moreover, we could segment 70 or 80 percent of those cells using hybrid watershed and region growing algorithm.
AB - Currently the existing computer analysis system for genomic drug discovery does not take it in to account that when cells are examined microscopically, excitation light or phosphor that is used on this occasion affects them adversely. We focused attention on phase microscope which can observe cells noninvasively. Until now, phase-contrast image has been difficult to process because recognition rate varies according to conditions, and for this, appropriate analyzing system has not been established. The study succeeded location of almost all cells. Moreover, we could segment 70 or 80 percent of those cells using hybrid watershed and region growing algorithm.
KW - Component
KW - Genomic drug discovery
KW - Image processing
KW - Phase microscope
UR - http://www.scopus.com/inward/record.url?scp=78649307316&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78649307316&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:78649307316
SN - 9784907764364
T3 - Proceedings of the SICE Annual Conference
SP - 84
EP - 88
BT - Proceedings of SICE Annual Conference 2010, SICE 2010 - Final Program and Papers
PB - Society of Instrument and Control Engineers (SICE)
ER -