Cell therapy for spinal cord injury using induced pluripotent stem cells

研究成果: Review article

抄録

For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.

元の言語English
ページ(範囲)75-80
ページ数6
ジャーナルRegenerative Therapy
11
DOI
出版物ステータスPublished - 2019 12 1

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Induced Pluripotent Stem Cells
Cell- and Tissue-Based Therapy
Stem cells
Spinal Cord Injuries
Cytology
Neurology
Pathology
Momentum
Transplantation
Recovery
Regenerative Medicine
Therapeutics
Cell Biology
Stem Cells
Central Nervous System
Research

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Developmental Biology

これを引用

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title = "Cell therapy for spinal cord injury using induced pluripotent stem cells",
abstract = "For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.",
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author = "Narihito Nagoshi and Osahiko Tsuji and Masaya Nakamura and Hideyuki Okano",
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AU - Nagoshi, Narihito

AU - Tsuji, Osahiko

AU - Nakamura, Masaya

AU - Okano, Hideyuki

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Y1 - 2019/12/1

N2 - For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.

AB - For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.

KW - Clinical application

KW - Induced pluripotent stem cells

KW - Neural precursor cells

KW - Spinal cord injury

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JO - Regenerative Therapy

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