Cellular and molecular mechanisms of neuronal migration in neocortical development

Takao Honda, Hidenori Tabata, Kazunori Nakajima

研究成果: Article査読

14 被引用数 (Scopus)

抄録

The complicated mammalian brain structure arises from accurate movements of neurons from their birthplace to their final locations. Detailed observation of this migration process by various methods revealed that neuronal migration is highly motile and that there are different modes of migration. Moreover, mouse mutants or human disorders that disrupt normal migration have provided significant insights into molecular pathways that control the neuronal migration. Although our knowledge is still fragmentary, it is becoming clear that various molecules are participating in this process. In this review, we outline about the cellular and molecular mechanisms of neuronal migration in the cerebral cortex.

本文言語English
ページ(範囲)169-174
ページ数6
ジャーナルSeminars in Cell and Developmental Biology
14
3
DOI
出版ステータスPublished - 2003 6月

ASJC Scopus subject areas

  • 発生生物学
  • 細胞生物学

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