Cellular variant of extraskeletal myxoid chondrosarcoma of abdominal wall - a case report with comparative immunohistochemical study on cartilaginous collagenous proteins in various myxoid mesenchymal tumors

Yoshimichi Ueda, Yasunori Okada, Isao Nakanishi

研究成果: Article査読

13 被引用数 (Scopus)

抄録

A rare cellular variant of recurrent extraskeletal myxoid chondrosarcoma occurring in the right lower abdominal wall of a 70-year-old man, is presented with emphasis on a characteristic distribution pattern of cartilaginous collagen proteins in the stroma. While the primary and the first recurrent tumors showed the typical histology of extraskeletal myxoid chondrosarcoma, the later tumor, which recurred 14 years after the first resection, comprised mostly compact nodules of proliferating anaplastic cells with little mucoid stroma. Some areas presented a hemangiopericytomatous pattern. A few nodules possessed abundant myxoid stroma. Immunohistochemically, type II collagen was demonstrated in the stroma of some cellular areas, and type VI collagen was intensely stained around individual tumor cells both in cellular and myxoid areas. In a comparative immunohistochemical study, the same distribution pattern of cartilaginous collagen proteins was observed only in skeletal myxoid chondrosarcomas, but not in other mesenchymal tumors with abundant myxoid stroma. These findings seem to support the cartilaginous nature of extraskeletal myxoid chondrosarcoma, and will facilitate the differential diagnosis of soft-tissue tumors with myxoid stroma.

本文言語English
ページ(範囲)147-151
ページ数5
ジャーナルJournal of Cancer Research and Clinical Oncology
118
2
DOI
出版ステータスPublished - 1992 2月
外部発表はい

ASJC Scopus subject areas

  • 腫瘍学
  • 癌研究

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